Physical properties, hygroscopicity and estimated pulmonary retention of various therapeutic aerosols.

The importance of this work centers around four considerations. The above-mentioned alterations in the assay of Stubbs and Kamovsky may lead to the elucidation of principles not possible with less efficient and less accurate methods. A second consideration is the maintenance of resting CPM sufficiently above background levels in order to reflect actual phagocytizing/resting ratios. This may not be possible with less efficient assays. A third consideration is that the improved assay method facilitates calculation of stoichiometric relationships such as quantitative oxygen uptake. Finally, increased efficiency and accuracy should make possible comparison of data produced by different investigators.